Blood flow through the mitral valve is essential for proper cardiovascular function. The mitral valve controls the flow between the atrium and the ventricle and its closure prevents regurgitation of blood into the atrium. Mitral pathologies can alter flow dynamics and affect valve function, highlighting the need to study its biomechanical behaviour.
This Master’s Thesis focuses of finite element (FEM) study of mitral valve function to simulate its closure. Using transesophageal echocardiography images obtained in collaboration with Hospital Universitario Puerta de Hierro of Majadahonda, the geometry of the valve will be reconstructed and high-resolution meshes will be generated to accurately represent the anatomy and biomechanical properties of the valve tissues.
The model has been implemented in Abaqus to analyse the stresses and strains in the valve leaflets and the proper closure of the valve.This has been done by means of transient analyses with different cases of evolving pressures representative of ventricular action. However, no fluid-structure type simulations have been included in this work. Three different tissue thicknesses have been studied in order to simulate the physiological condition and two pathological situations simulated by increasing the thickness but not the stiffness of the material. The 1 millimetre case represents the physiological situation of a patient while the 2 millimetre case represents a moderate pathological situation and the 3 millimetre case represents a severe pathological situation.
The results of this study are expected to contribute to a better understanding of mitral valve biomechanics and serve as a basis for improved medical interventions and valve prosthesis design.
Blood flow through the mitral valve is essential for proper cardiovascular function. The mitral valve controls the flow between the atrium and the ventricle and its closure prevents regurgitation of blood into the atrium. Mitral pathologies can alter flow dynamics and affect valve function, highlighting the need to study its biomechanical behaviour.
This Master’s Thesis focuses of finite element (FEM) study of mitral valve function to simulate its closure. Using transesophageal echocardiography images obtained in collaboration with Hospital Universitario Puerta de Hierro of Majadahonda, the geometry of the valve will be reconstructed and high-resolution meshes will be generated to accurately represent the anatomy and biomechanical properties of the valve tissues.
The model has been implemented in Abaqus to analyse the stresses and strains in the valve leaflets and the proper closure of the valve.This has been done by means of transient analyses with different cases of evolving pressures representative of ventricular action. However, no fluid-structure type simulations have been included in this work. Three different tissue thicknesses have been studied in order to simulate the physiological condition and two pathological situations simulated by increasing the thickness but not the stiffness of the material. The 1 millimetre case represents the physiological situation of a patient while the 2 millimetre case represents a moderate pathological situation and the 3 millimetre case represents a severe pathological situation.
The results of this study are expected to contribute to a better understanding of mitral valve biomechanics and serve as a basis for improved medical interventions and valve prosthesis design. Read More
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